Adiponectin, globular domain protein (30R-1047)
Purified recombinant Mouse Adiponectin, globular domain protein
|Synonyms||Gelatin binding protein protein, ACRP30 protein, Mouse protein, Adiponectin protein, Adipocyte complement related protein of 30 kDa protein, Adipose most abunda protein, 30 kDa adipocyte complement-related protein protein, Adipocyte C1q and collagen domain containing protein protein, Adipocyte complement-related 30 kDa protein protein, C1q and collagen domain-containing protein protein, Adiponectin globular domain protein, ACRP 30 protein, GBP 28 protein, APM1 protein, APM 1 protein, Adipose most abundant gene transcript 1 protein, ACRP30 protein, , ACDC protein, Adipocyte complement related 30 kDa protein protein, 30 kDa adipocyte complement related protein protein, Adipocyte protein, ADIPOQ protein, GBP28 protein|
Coomassie Blue stained SDS-PAGE of Adiponectin, globular domain protein (30R-1047)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||111-247 amino acids: MAYMYRSAFS VGLETRVTVP NVPIRFTKIF YNQQNHYDGS TGKFYCNIPG LYYFSYHITV YMKDVKVSLF KKDKAVLFTY DQYQEKNVDQ ASGSVLLHLE VGDQVWLQVY GDGDHNGLYA DNVNDSTFTG FLLYHDTN|
|Grade & Purity||> 95% pure|
|Molecular Weight||16 kDa (138 aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl, pH7.5, containing 50mM NaCl, 5mM DTT, and 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||Adiponectin/Acrp30 (247 amino acids) is adipocyte complement-related protein of 30kDa and exclusively expressed in differentiated adipocytes. Adiponectin (Acrp30) is a member of the complement factor C1q family and consists of signal sequence, non-homologous sequence, collagen domain and globular domain (gAcrp30). Adiponectin (Acrp30) expression is reduced in a variety of obese and insulin-resistant states in human, monkeys and mice. Injection of Acrp30 (247 amino acids) or gAcrp30 (globular domain) lowers serum glucose and free fatty acid level in mice. The globular domain of adiponectin/acrp30 (amino acid residues, 111-247, gAcrp30) was overexpressed in E. coli and purified by using conventional chromatography techniques.|
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