ADRA1B antibody (70R-9950)
Affinity purified rabbit polyclonal ADRA1B antibody
|Synonyms||Polyclonal ADRA1B antibody, Anti-ADRA1B antibody, ADRA1 antibody, adrenergic, ADRAB-1, ALPHA1BAR antibody, receptor antibody, alpha-1B-, ADRAB 1 antibody, ADRAB 1, ADRAB-1 antibody, ADRA1B|
|Immunogen||ADRA1B antibody was raised in rabbit using the C terminal of ADRA1B as the immunogen|
|Assay Information||ADRA1B Blocking Peptide, catalog no. 33R-10230, is also available for use as a blocking control in assays to test for specificity of this ADRA1B antibody|
Western Blot analysis using ADRA1B antibody (70R-9950)
ADRA1B antibody (70R-9950) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.|
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