ADRA1B antibody (70R-9951)
Affinity purified rabbit polyclonal ADRA1B antibody
|Synonyms||Polyclonal ADRA1B antibody, Anti-ADRA1B antibody, ADRAB-1, alpha-1B-, ADRA1 antibody, ALPHA1BAR antibody, ADRAB 1 antibody, ADRA1B, adrenergic, ADRAB 1, receptor antibody, ADRAB-1 antibody|
|Immunogen||ADRA1B antibody was raised in rabbit using the N terminal of ADRA1B as the immunogen|
|Assay Information||ADRA1B Blocking Peptide, catalog no. 33R-9914, is also available for use as a blocking control in assays to test for specificity of this ADRA1B antibody|
Western Blot analysis using ADRA1B antibody (70R-9951)
Western Blot showing ADRA1B antibody used at a concentration of 1-2 ug/ml to detect its target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene.|
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