ADSL antibody (70R-9952)

Affinity purified rabbit polyclonal ADSL antibody

Synonyms Polyclonal ADSL antibody, Anti-ADSL antibody, AMPS antibody, ASASE antibody, ASL antibody, adenylosuccinate lyase antibody
Cross Reactivity Human
Applications WB
Immunogen ADSL antibody was raised in rabbit using the middle region of ADSL as the immunogen
Assay Information ADSL Blocking Peptide, catalog no. 33R-8172, is also available for use as a blocking control in assays to test for specificity of this ADSL antibody

Images

Western Blot analysis using ADSL antibody (70R-9952)

ADSL antibody (70R-9952) used at 0.2-1 ug/ml to detect target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene.

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Images

  • Western Blot analysis using ADSL antibody (70R-9952) | ADSL antibody (70R-9952) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: £276.43
Size: 50 ug
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