AKR1C1 antibody (70R-10004)
Affinity purified rabbit polyclonal AKR1C1 antibody
|Synonyms||Polyclonal AKR1C1 antibody, Anti-AKR1C1 antibody, C9 antibody, 3-alpha-hydroxysteroid dehydrogenase antibody, DDH antibody, MGC8954 antibody, AKRC 1, DD1 antibody, aldo-keto reductase family 1, 2-ALPHA-HSD antibody, AKRC 1 antibody, AKRC-1 antibody, H-37 antibody, 20-ALPHA-HSD antibody, HAKRC antibody, MBAB antibody, AKRC-1, DDH1 antibody, dihydrodiol dehydrogenase 1; 20-alpha, member C1, AKR1C1|
|Immunogen||AKR1C1 antibody was raised in rabbit using the N terminal of AKR1C1 as the immunogen|
|Assay Information||AKR1C1 Blocking Peptide, catalog no. 33R-2154, is also available for use as a blocking control in assays to test for specificity of this AKR1C1 antibody|
Western Blot analysis using AKR1C1 antibody (70R-10004)
Western Blot showing AKR1C1 antibody used at a concentration of 1-2 ug/ml to detect its target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.|
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