ANXA8 protein (His tag) (80R-1444)

Purified recombinant Human ANXA8 protein

Synonyms ANXA8, Annexin A8, ANX8 protein, ANXA 8, VAC-beta protein, ANXA 8 protein, ANXA-8 protein, Annexin VII protein, Annexin-8 protein, ANXA-8, Vascular anticoagulant-beta protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of ANXA8 protein (His tag) (80R-1444)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 1-327 amino acids: MGSSHHHHHH SSGLVPRGSH MAWWKSWIEQ EGVTVKSSSH FNPDPDAETL YKAMKGIGTN EQAIIDVLTK RSNTQRQQIA KSFKAQFGKD LTETLKSELS GKFERLIVAL MYPPYRYEAK ELHDAMKGLG TKEGVIIEIL ASRTKNQLRE IMKAYEEDYG SSLEEDIQAD TSGYLERILV CLLQGSRDDV SSFVDPGLAL QDAQDLYAAG EKIRGTDEMK FITILCTRSA THLLRVFEEY EKIANKSIED SIKSETHGSL EEAMLTVVKC TQNLHSYFAE RLYYAMKGAG TRDGTLIRNI VSRSEIDLNL IKCHFKKMYG KTLSSMIMED TSGDYKNALL SLVGSDP
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 39.0 kDa (347aa), confirmed by MALDI-TOF
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 0.1M NaCl, 1mM DTT, 1mM EDTA and 10% glycerol.
Concentration 1 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance ANXA8, also known as Annexin A8, a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. Where co-expressed in the same tissues, ANXA8 is often expressed at a 100-fold lower level than Annexin A5. However, ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate to its role in hematopoietic cell differentiation. Recombinant human ANXA8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

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Images

  • Coomassie Blue stained SDS-PAGE of ANXA8 protein (His tag) (80R-1444) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £236.37
Size: 100 ug
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