APP antibody (20C-CR1088GP)

Goat polyclonal APP antibody

Synonyms Polyclonal APP antibody, Anti-APP antibody, Amyloid Precursor Protein antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications ELISA
Immunogen APP antibody was raised in goat using a synthetic peptide corresponding to amino acids 44-63 of the N-terminus of the alzheimer's disease APP as the immunogen.

Specifications

Host Goat
Form & Buffer PBS, pH 7.4 with 0.05% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations ELISA: 1:5,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Amyloid precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. Its primary function is not known, though it has been implicated as a regulator of synapse formation, neural plasticity and iron export. APP is best known and most commonly studied as the precursor molecule whose proteolysis generates beta amyloid (ABeta), a 39- to 42-amino acid peptide whose amyloid fibrillar form is the primary component of amyloid plaques found in the brains of Alzheimer's disease patients.

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Availability: In stock

Price: £175.47
Size: 1 mg
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