ARL2 protein (His tag) (80R-1604)
Purified recombinant Human ARL2 protein
|Synonyms||ARL-2, ARL2, ARFL2, ARL 2 protein, ARL 2, ADP-ribosylation factor-like protein 2 protein, ARL-2 protein|
Coomassie Blue stained SDS-PAGE of ARL2 protein (His tag) (80R-1604)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-184 amino acids: MGSSHHHHHH SSGLVPRGSH MGLLTILKKM KQKERELRLL MLGLDNAGKT TILKKFNGED IDTISPTLGF NIKTLEHRGF KLNIWDVGGQ KSLRSYWRNY FESTDGLIWV VDSADRQRMQ DCQRELQSLL VEERLAGATL LIFANKQDLP GALSSNAIRE ALELDSIRSH HWCIQGCSAV TGENLLPGID WLLDDISSRI FTAD|
|Grade & Purity||> 90% pure|
|Molecular Weight||23.0 kDa(204aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0.1mM PMSF, 1mM DTT and 40% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||ARL2 belongs to the ADP-ribosylation factor (ARF) family. This protein functions as a component of a secretory pathway that is involved in the Ca2-dependent release of acetylcholine. It plays a role in the folding of tubule proteins, thereby playing an important role in microtubule dynamics and cell cycle progression. Unlike other members of the ARF family, ARL2 does not act as an activator of the catalytic subunit of cholera toxin. Recombinant human ARL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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