ARL2BP protein (His tag) (80R-1526)
Purified recombinant Human ARL2BP protein
|Synonyms||ARL2BP, ARLBP 2 protein, ARLBP-2 protein, BART protein, ADP-ribosylation factor-like 2 binding protein protein, ARLBP 2, BART1, ARLBP-2|
Coomassie Blue stained SDS-PAGE of ARL2BP protein (His tag) (80R-1526)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-163 amino acids: MGSSHHHHHH SSGLVPRGSH MDALEGESFA LSFSSASDAE FDAVVGYLED IIMDDEFQLL QRNFMDKYYL EFEDTEENKL IYTPIFNEYI SLVEKYIEEQ LLQRIPEFNM AAFTTTLQHH KDEVAGDIFD MLLTFTDFLA FKEMFLDYRA EKEGRGLDLS SGLVVTSLCK SSSLPASQNN LRH|
|Grade & Purity||> 90% pure|
|Molecular Weight||20.9 kDa (183aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||ARL2BP is an effector of ADP-ribosylation factor-like 2 (ARL2) that is essential for nuclear retention of STAT3. This protein binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. Though predominantly cytosolic, ARL2BP can enter the mitochondria and bind the adenine nucleotide transporter when bound to ARL2. Thus it may also be involved in mitochondria transport and apoptosis. Recombinant human ARL2BP protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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