BDNF antibody (70R-BR012)

Affinity purified Rabbit polyclonal BDNF antibody

Synonyms Polyclonal BDNF antibody, Anti-BDNF antibody, Brain Derived Neurotrophic Factor antibody
Specificity Human BDNF
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen BDNF antibody was raised in rabbit using highly pure recombinant human BDNF as the immunogen.

Specifications

Host Rabbit
Molecular Weight 27 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations ELISA: 0.5-2 ug/ml, Inhibition: 0.54-0.81 ug/ml, WB: 0.1-0.2 ug/ml

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/tr kb. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residue and a propeptide of 110 amino acid residues.

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Availability: In stock

Price: £180.28
Size: 50 ug
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