beta Amyloid antibody (10R-A124a)

Mouse monoclonal beta Amyloid antibody

Synonyms Monoclonal beta Amyloid antibody, Anti-beta Amyloid antibody, Alzheimer Precursor Protein A4 antibody, Ab antibody, Amyloid beta antibody, APP-A4 antibody, Abeta antibody, Amyloid Plaque antibody
Cross Reactivity Dog, fish, human, monkey, mouse, pig, Rat
Applications IF, IHC, WB
Immunogen Beta amyloid antibody was raised in mouse using purified recombinant alzheimer precursor A4 fusion protein as the immunogen.

Images

Immunohistochemical staining using beta Amyloid antibody (10R-A124a)

Amyloid (Abeta) staining on Alzheimer’s Disease-Hypothalamus. Tissue pretreated with Citrate, pH 6.0. beta Amyloid antibody was diluted to 1:80. Immunoreactivity is seen as staining on plaque deposits (dark brown).

Specifications

Host Mouse
Clone 22C11
Isotype IgG1
Form & Buffer 20mM PO4 buffer, with 0.25M NaCl, and 0.1% NaN3.
Concentration 1.0 mg/ml

Usage & Assay Information

Usage Recommendations IHC: 5-10 ug/ml, WB: 10 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Deposits of amyloid protein in senile plaques near nerve processes are found in the brains of aged humans and cases of Alzheimer's Disease. The principle component of this extracellular amyloid is beta A4, a 4 kDa peptide derived from a larger amyloid precursor protein (APP), which is widely expressed in the brain and body. The creation, transport and function of these proteins is currently an active area of research.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Immunohistochemical staining using beta Amyloid antibody (10R-A124a) | Amyloid (Abeta) staining on Alzheimer’s Disease-Hypothalamus. Tissue pretreated with Citrate, pH 6.0. beta Amyloid antibody was diluted to 1:80. Immunoreactivity is seen as staining on plaque deposits (dark brown).
  • Immunohistochemical staining using beta Amyloid antibody (10R-A124a) | Amyloid (Abeta) staining on Alzheimer’s Disease-Hypothalamus (left). Tissue pretreated with Citrate, pH 6.0. beta Amyloid antibody diluted to 1:80. Immunoreactivity is seen as cerebral vascular amyloid deposition in the walls of blood vessels (brown). Negative Control staining on Alzheimer’s Disease-Hypothalamus (right). Tissue pretreated with Citrate, pH 6.0.
  • Immunohistochemical staining using beta Amyloid antibody (10R-A124a) | Negative Control staining on Alzheimer’s Disease-Hypothalamus. Tissue pretreated with Citrate, pH 6.0. Negative Control Reagent, IHC-Select Detection with HRP-DAB.
  • Western blot analysis using beta Amyloid antibody (10R-A124a) | APP antibody western blot of endogenous APPs from SH-SY5Y conditioned medium.

Availability: In stock

Price: £492.77
Size: 50 ug
OR
Shipping
View Our Distributors