beta NGF protein (30R-AB039)

Purified recombinant Human beta NGF protein

Synonyms beta-NGF protein, NGF-beta protein, Nerve Growth factor protein
Species Human
Protein Type Recombinant
Applications User optimized

Specifications

Residues Region of Beta NGF protein corresponding to amino acids MSSTHPVFHM GEFSVCDSVS VWVGDKTTAT DIKGKEVTVL AEVNINNSVF RQYFFETKCR ASNPVESGCR GIDSKHWNSY CTTTHTFVKA LTTDEKQAAW RFIRIDTACV CVLSRKATRR G.
Expression System E.coli
Grade & Purity > 98% pure
Molecular Weight 13.4 kDa
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels Endotoxin level is less than 0.1 ng per ug (1 EU/ug).

General Information

Biological Significance beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. beta-NGF is a potent neurotrophic factor that signals through its receptor beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival.

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Availability: In stock

Price: £180.28
Size: 20 ug
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