BMP4 protein (30R-1255)

Purified recombinant Human BMP4 protein

Synonyms Bone morphogenetic protein 4 BMP 4 protein, BMP 4 protein, DVR4 protein, BMP 4, BMP-4 protein, BMP-4, BMP-2B protein, BMP4, ZYME., BMP2B1 protein, BMP2B protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of BMP4 protein (30R-1255)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 293-408 amino acids: MSPKHHSQRA RKKNKNCRRH SLYVDFSDVG WNDWIVAPPG YQAFYCHGDC PFPLADHLNS TNHAIVQTLV NSVNSSIPKA CCVPTELSAI SMLYLDEYDK VVLKNYQEMV VEGCGCR
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 13.2 kDa (117 aa), confirmed by MALDI-TOF.
Form & Buffer Supplied as a liquid in 10mM sodium citrate buffer, pH 3.5, containing 10% glycerol.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance Bone morphogenetic protein 4 (BMP-4) is a member of the bone morphogenetic protein family which belongs to the TGF-beta superfamily. This protein is a vital regulatory molecule that functions throughout bone and cartilage development, specifically tooth development, limb formation, bone induction, and fracture repair. In human embryonic development, BMP- 4 is required for the early differentiation of the embryo and establishing of a dorsal-ventral axis. And it is overexpressed in patients with fibrodysplasia ossificans progressiva. Recombinant BMP-4 was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Images

  • Coomassie Blue stained SDS-PAGE of BMP4 protein (30R-1255) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £144.23
Size: 100 ug
OR
Shipping
View Our Distributors