BMP5 protein (30R-1350)
Purified recombinant Human BMP5 protein
|Synonyms||BMP5, Bone morphogenetic protein 5 BMP 5 protein, BMP 5 protein, , BMP-5 protein, MGC34244 protein, BMP-5 protein, BMP-5, BMP 5|
Coomassie Blue stained SDS-PAGE of BMP5 protein (30R-1350)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||317-454 amino acids: MAANKRKNQN RNKSSSHQDS SRMSSVGDYN TSEQKQACKK HELYVSFRDL GWQDWIIAPE GYAAFYCDGE CSFPLNAHMN ATNHAIVQTL VHLMFPDHVP KPCCAPTKLN AISVLYFDDS SNVILKKYRN MVVRSCGCH|
|Grade & Purity||> 95% pure|
|Molecular Weight||15.7 kDa (139aa), confirmed by MALDI-TOF.|
|Form & Buffer||Supplied as a liquid in 10mM sodium citrate buffer, pH 3.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||BMP5 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. BMP5 may play a role in certain cancers. This protein may act as a important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. Recombinant BMP5 was expressed in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.|
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