BMP7 protein (His tag) (80R-1107)

Purified recombinant Human BMP7 protein

Synonyms OP-1 protein, BMP 7 protein, BMP-7 protein, Osteogenic protein1 protein, BMP-7, Bone morphogenetic protein 7 BMP 7 protein, Eptotermin alfa protein, BMP 7, BMP7, OP 1 protein, OP1.
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Images

Coomassie Blue stained SDS-PAGE of BMP7 protein (His tag) (80R-1107)

Figure annotation denotes ug of protein loaded and % gel used.

Specifications

Residues 293-431 amino acids: MSTGSKQRSQ NRSKTPKNQE ALRMANVAEN SSSDQRQACK KHELYVSFRD LGWQDWIIAP EGYAAYYCEG ECAFPLNSYM NATNHAIVQT LVHFINPETV PKPCCAPTQL NAISVLYFDD SSNVILKKYR NMVVRACGCH LEHHHHHH
Expression System E.coli
Grade & Purity > 95% pure
Molecular Weight 16.8 kDa (148 aa), confirmed by MALDI-TOF.
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 10mM sodium citrate buffer, pH 3.5, containing 10% glycerol.
Concentration 0.5 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Endotoxin Levels < 1.0 EU per ug of protein (determined by LAL method)

General Information

Biological Significance Bone morphogenic protein-7 (BMP-7/OP-1) is a member of the transforming growth factor-beta (TGF-beta) superfamily. Like other members of the BMPs family, it plays a role in calcium regulation and bone homeostasis. BMPs have been also shown to regulate the growth, differentiation, chemotaxis and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells and neuronal cells. BMP7 also has the potential for treatment of chronic kidney disease. Recombinant human BMP-7 protein was expressed in E. coli and purified by using conventional chromatography techniques, after refolding of the isolated inclusion body in renaturation buffer.

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Images

  • Coomassie Blue stained SDS-PAGE of BMP7 protein (His tag) (80R-1107) | Figure annotation denotes ug of protein loaded and % gel used.

Availability: In stock

Price: £144.23
Size: 100 ug
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