BTBD12 antibody (70R-9912)
Affinity purified rabbit polyclonal BTBD12 antibody
|Synonyms||Polyclonal BTBD12 antibody, Anti-BTBD12 antibody, BTBD12, KIAA1784 antibody, BTBD 12 antibody, SLX4 antibody, KIAA1987 antibody, MUS312 antibody, BTBD-12, BTB, BTBD 12, POZ domain containing 12 antibody, BTBD-12 antibody|
|Immunogen||BTBD12 antibody was raised in rabbit using the N terminal of BTBD12 as the immunogen|
|Assay Information||BTBD12 Blocking Peptide, catalog no. 33R-9152, is also available for use as a blocking control in assays to test for specificity of this BTBD12 antibody|
Western Blot analysis using BTBD12 antibody (70R-9912)
Western Blot showing BTBD12 antibody used at a concentration of 1-2 ug/ml to detect its target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.|
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