C Peptide protein (30-AC96)

Purified recombinant Human C Peptide protein

Synonyms Proinsulin connecting peptide, C-Peptide protein
Species Human
Protein Type Synthetic
Applications User optimized

Specifications

Residues Region of C Peptide protein corresponding to amino acids Arg-Arg-Glu-Ala-Glu-Asp-Leu-Gln-Val-Gly-Gln-Val-Glu-Leu-Gly-Gly-Gly-Pro-Gly-Ala-Gly-Ser-Leu-Gln-Pro-Leu-Ala-Leu-Glu-Gly-Ser-Leu-Gln-Lys-Arg.
Source Human (full length synthetic C-peptide) Tyr-C-Peptide
Grade & Purity > 98% pure
Molecular Weight 3616.99 kDa
Form & Buffer Supplied as a lyophilized powder purified by HPLC, tyrosine residue.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance Proinsulin C-peptide was first described in 1967 in connection with the discovery of the insulin biosynthesis. It serves as an important linker between the A- and the B- chains of insulin and facilitates the efficient assembly, folding, and processing of insulin in the endoplasmic reticulum. Equimolar amounts of C-peptide and insulin are then stored in secretory granules of the pancreatic beta cells and both are eventually released to the portal circulation. Initially, the sole interest in C-peptide was as a marker of insulin secretion and has as such been of great value in furthering the understanding of the pathophysiology of type 1 and type 2 diabetes. The first documented use of the C-peptide test was in 1972. During the past decade, however, C-peptide has been found to be a bioactive peptide in its own right, with effects on microvascular blood flow and tissue health.

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Availability: In stock

Price: £360.56
Size: 100 ug
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