CALB1 antibody (70R-9983)

Affinity purified rabbit polyclonal CALB1 antibody

Synonyms Polyclonal CALB1 antibody, Anti-CALB1 antibody, CALB antibody, 28kDa antibody, CALB1, CALB 1 antibody, CALB 1, CALB-1, calbindin 1, CALB-1 antibody
Cross Reactivity Human
Applications WB
Immunogen CALB1 antibody was raised in rabbit using the C terminal of CALB1 as the immunogen
Assay Information CALB1 Blocking Peptide, catalog no. 33R-2409, is also available for use as a blocking control in assays to test for specificity of this CALB1 antibody

Images

Immunohistochemical staining using CALB1 antibody (70R-9983)

Calbindin 1 in Purkinje neurons in human cerebellum was detected using HRP/DAB brown color stain

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted.

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Images

  • Immunohistochemical staining using CALB1 antibody (70R-9983) | Calbindin 1 in Purkinje neurons in human cerebellum was detected using HRP/DAB brown color stain
  • Western Blot analysis using CALB1 antibody (70R-9983) | Western Blot showing CALB1 antibody used at a concentration of 1.0 ug/ml against COLO205 Cell Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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