Cathepsin G protein (30-AC72)

Purified native Human Cathepsin G protein

Species Human
Protein Type Native
Applications User optimized

Specifications

Source Human neutrophils
Grade & Purity > 95% pure
Molecular Weight 23.5 Da
Form & Buffer Salt-free lyophilized solid. Reconstitute with 50mM CH3COONa, pH 5.5, with 150mM NaCl.

Usage & Assay Information

Bioactivity 2-4 units/mg - One unit of activity is defined as the amount of enzyme that hydrolyzes one micromole of Suc-ala-ala-pro-phe-pNA (1mM) per minute at 25o C in 160 mM Tris-HCl, pH 7.4, with 1.6 M NaCl.

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles.
Biohazard Information Donor samples were tested and found to be negative for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2. Nonetheless caution should be used when handling this material as there is a margin of error in all tests.

General Information

Biological Significance Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSG gene. This enzyme degrades collagen and proteoglycan and can also cause the release of angiotensin II from angiotensin I or angiotensinogen. It has been implicated in connective tissue diseases such as emphysema and rheumatoid arthritis.

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Availability: In stock

Price: £268.82
Size: 100 ug
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