CCL13 protein (His tag) (80R-1458)
Purified recombinant Human CCL13 protein
|Synonyms||NCC-1 protein, CKb10 protein, ckbeta10, C-C motif chemokine 13 protein, CCL 13 protein, CCL-13, CCL 13, Small-inducible cytokine A13 protein, SCYL1 protein, MCP-4 protein, CCL13, MCP4 protein, CCL-13 protein, SCYA1 protein, C-C motif chemokine 13 protein, CK-beta-10 protein, NCC1 protein, chemokine (C-C motif) ligand 13 protein|
Coomassie Blue stained SDS-PAGE of CCL13 protein (His tag) (80R-1458)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||24-98 amino acids: MGSSHHHHHH SSGLVPRGSH MQPDALNVPS TCCFTFSSKK ISLQRLKSYV ITTSRCPQKA VIFRTKLGKE ICADPKEKWV QNYMKHLGRK AHTLKT|
|Grade & Purity||> 90% pure|
|Molecular Weight||10.8 kDa (96aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in PBS, pH 7.4, containing 10% glycerol, 0.1M NaCl, and 1mM DTT.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||CCL13 is a small cytokine belonging to the CC chemokine family that is also known as thymus and activation regulated chemokine (TARC). This protein induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. It can be induced by the inflammatory cytokines interleukin-1 and TNF-alpha. Recombinant human CCL13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.|
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