CCL3 protein (His tag) (80R-1776)

Purified recombinant Human CCL3 protein

Synonyms G0S19-1 protein, CCL3, CCL 3 protein, CCL 3, C-C motif chemokine 3 protein, LD78ALPHA. MIP-1-alpha. MIP1A. SCYA3 protein, CCL-3, CCL-3 protein
Species Human
Protein Type Recombinant
Applications SDS-PAGE

Specifications

Residues 24-92 amino acids: MGSSHHHHHH SSGLVPRGSH MSLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPGV IFLTKRSRQV CADPSEEWVQ KYVSDLELSA
Expression System E.coli
Grade & Purity > 90% pure
Molecular Weight 10.0 kDa (90aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Tag/Conjugate His tag
Form & Buffer Supplied as a liquid in 10mM sodium citrate, pH 3.5, containing 10% glycerol.
Concentration 0.25 mg/ml

Storage & Safety

Storage Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CCL3, also known as, macrophage inflammatory protein-1alpha (MIP-1alpha), is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes. This protein has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1beta and RANTES. It acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner. Recombinant human CCL3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purifed by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.

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Availability: In stock

Price: £272.43
Size: 50 ug
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