CD115 antibody (BSA/Azide Free) (10R-CD115aP)

Rat monoclonal CD115 antibody (BSA/Azide Free)

Synonyms Monoclonal CD115 antibody, Anti-CD115 antibody, CD115, CD-115 antibody, CD 115, CD 115 antibody, CD-115
Specificity Human
Cross Reactivity To be determined by end-user
Applications IF, IHC
Immunogen CD115 antibody (BSA/Azide-free) was raised in rat using v-ras-transformed rat NRK cells expressing transduced human CSF-1R as the immunogen.

Specifications

Host Rat
Clone 2-4A5-4
Isotype IgG1 kappa
Method of Purification CD115 antibody (BSA/Azide Free)
Form & Buffer Antibody purified from ascites fluid by ammonium sulfate precipitation and supplied in 10mM PBS, pH 7.4.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.

General Information

Biological Significance CD115, also known as c-fms, macrophage Colony Stimulating Factor Receptor (MCSFR), or CSF-1R, exists in immature (gp130c-fms) and mature (gp150c-fms) forms. CSF-1R exhibits an intrinsic tyrosine-specific protein kinase activity. It is expressed on the cells of the mononuclear phagocyte lineage. CSF-1R is an integral transmembrane glycoprotein consisting of a 512 amino acid extracellular domain that includes the CSF-1 binding site, a single 25 amino acid membrane-spanning segment, and a 435 amino acid cytoplasmic portion that includes the tyrosine kinase domain.

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Availability: In stock

Price: £500.78
Size: 200 ul
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