CD141 antibody (10R-CD141b)

Mouse monoclonal CD141 antibody

Synonyms Monoclonal CD141 antibody, Anti-CD141 antibody, CD141, CD-141 antibody, CD 141, CD 141 antibody, CD-141
Specificity Human
Cross Reactivity Rabbit
Applications FC, IHC-F, IHC-P
Immunogen CD141 antibody was raised in mouse using human endothelium (Thrombomodulin) as the immunogen.

Specifications

Host Mouse
Clone QBEND/40
Isotype IgG2a
Form & Buffer Tissue culture supernatant supplied in 0.2M tris-HCl, pH7.4 with 5-10% FCS with 0.09% NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations FC: Neat, IHC-F: 1:10-1:100, IHC-P: 1:10-1:50

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Thrombomodulin, CD141 or BDCA-3 is an integral membrane protein expressed on the surface of endothelial cells. In humans, thrombomodulin is encoded by the THBD gene. The protein has a molecular mass of 74 kDa, and consists of a single chain with 5 distinct domains. It functions as a cofactor in the thrombin-induced activation of protein C in the anticoagulant pathway by forming a 1:1 stoichiometric complex with thrombin. This raises the speed of protein C activation thousandfold.

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Availability: In stock

Price: £356.56
Size: 1 ml
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