CD25 antibody (Azide Free) (10R-CD25dMSP)

Rat monoclonal CD25 antibody (Azide Free)

Synonyms Monoclonal CD25 antibody, Anti-CD25 antibody, IL2Ra antibody, CD25 IL2-R alpha TAC antibodyIL2-R alpha TAC antibody, CD 25, CD 25 antibody, CD25, CD-25 antibody, CD-25
Specificity Murine CD25
Cross Reactivity To be determined by end-user
Applications FC, IP
Immunogen CD25 antibody (Azide free) was raised in rat using IL-2-dependent BALB/c mouse helper T-cell as the immunogen.

Specifications

Host Rat
Clone 7D4
Isotype IgM
Form & Buffer Supplied as a liquid in PBS.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles

General Information

Biological Significance CD25 is the alpha chain of the IL-2 receptor. It is a type I transmembrane protein present on activated T cells, activated B cells, some thymocytes, myeloid precursors, and oligodendrocytes that associates with CD122 to form a heterodimer that can act as a high-affinity receptor for IL-2. CD25 is expressed in most B-cell neoplasms, some acute nonlymphocytic leukemias, neuroblastomas, and tumor infiltrating lymphocytes. Its soluble form, called sIL-2R may be elevated in these diseases and is occasionally used to track disease progression.

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Availability: In stock

Price: £316.49
Size: 500 ug
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