CD40L antibody (70R-CR026)

Affinity purified Rabbit polyclonal CD40L antibody

Synonyms Polyclonal CD40L antibody, Anti-CD40L antibody, CD40L, TRAP antibody, CDL 40 antibody, CDL-40 antibody, TNFSF5 antibody, T-BAM antibody, CD154 antibody, soluble CD40 Ligand antibody, CDL 40, gp39 antibody, CDL-40
Specificity Human CD40L
Cross Reactivity To be determined by end-user
Applications ELISA, Inhibition, WB
Immunogen CD40L antibody was raised in rabbit using highly pure recombinant human sCD40L as the immunogen.

Specifications

Host Rabbit
Molecular Weight 16.3 kDa (predicted detection band MW)
Form & Buffer Lyophilized from PBS, pH 7.2.

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at -20 deg C until reconstitution. Following reconstitution product may be stored at 4 deg C in the short term. For long term storage aliquot and freeze at -20 deg C. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CD40, a member of the TNF receptor family, is a cell surface protein expressed on B cells, dendritic cells, monocytes, thymic epithelial cells and, at low levels, on T cells. Signaling though CD40 plays an important role in the proliferation and differentiation of B cells, and is critical for immunoglobulin (Ig) class switching. The membrane-anchored CD40-Ligand is expressed almost exclusively on activated CD4+ T lymphocytes. Failure to express CD40L leads to "immunodeficiency with hyper-IgM", a disease characterized by failure to produce IgG, IgA and IgE. The human CD40L gene codes for a 261 amino acid type II transmembrane protein, which contains a 22 amino acid cytoplasmic domain, a 24 amino acid transmembrane domain, and a 215 amino acid extracellular domain.

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Availability: In stock

Price: £180.28
Size: 50 ug
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