CD8a antibody (biotin) (61R-CD8abMSBT)

Rat monoclonal CD8a antibody (biotin)

Synonyms Monoclonal CD8a antibody, Anti-CD8a antibody, CD8a, CD 8a antibody, CD-8a antibody, CD-8a, CD 8a, Ly2 antibody
Specificity Murine CD8a
Cross Reactivity To be determined by end-user
Applications FC, IHC, IP
Immunogen CD8a antibody (biotin) was raised in rat using murine thymus or spleen as the immunogen.

Specifications

Host Rat
Clone 53-6.7
Isotype IgG2a
Tag/Conjugate Biotin
Form & Buffer Supplied as a liquid in PBS, with NaN3 added as preservative.
Concentration 0.5 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by end user

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance CD8a (Cluster of Differentiation 8a), is a human gene. The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified.

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Availability: In stock

Price: £252.39
Size: 500 ug
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