CERKL antibody (70R-9906)

Affinity purified rabbit polyclonal CERKL antibody

Synonyms Polyclonal CERKL antibody, Anti-CERKL antibody, RP26 antibody, ceramide kinase-like antibody
Cross Reactivity Human
Applications WB
Immunogen CERKL antibody was raised in rabbit using the C terminal of CERKL as the immunogen
Assay Information CERKL Blocking Peptide, catalog no. 33R-1539, is also available for use as a blocking control in assays to test for specificity of this CERKL antibody

Images

Western Blot analysis using CERKL antibody (70R-9906)

CERKL antibody (70R-9906) used at 0.2-1 ug/ml to detect target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.

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Images

  • Western Blot analysis using CERKL antibody (70R-9906) | CERKL antibody (70R-9906) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: £276.43
Size: 50 ug
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