CHP protein (His tag) (80R-1360)
Purified recombinant Human CHP protein
|Synonyms||Calcium binding protein CHP protein, Calcineurin B homolog protein, Sid470 protein, SLC9A1 binding protein protein, SLC9A1BP protein, Wrch2, Calcium-binding protein p22 protein, Calcineurin homologous protein protein, Sid 470 protein|
Coomassie Blue stained SDS-PAGE of CHP protein (His tag) (80R-1360)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-195 amino acids: MGSSHHHHHH SSGLVPRGSH MMGSRASTLL RDEELEEIKK ETGFSHSQIT RLYSRFTSLD KGENGTLSRE DFQRIPELAI NPLGDRIINA FFPEGEDQVN FRGFMRTLAH FRPIEDNEKS KDVNGPEPLN SRSNKLHFAF RLYDLDKDEK ISRDELLQVL RMMVGVNISD EQLGSIADRT IQEADQDGDS AISFTEFVKV LEKVDVEQKM SIRFLH|
|Grade & Purity||> 95% pure|
|Molecular Weight||24.7 kDa(216aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 7.5, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||CHP (Calcium-binding protein P22) is a phosphoprotein that binds to the sodium-hydrogen exchangers (NHEs). This protein serves as an essential cofactor which supports the physiological activity of NHE family members. It has protein sequence similarity to calcineurin B and it is also known to be an endogenous inhibitor of calcineurin activity. Recombinant human CHP, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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