CHRNA4 antibody (70R-5185)

Rabbit polyclonal CHRNA4 antibody raised against the N terminal of CHRNA4

Synonyms Polyclonal CHRNA4 antibody, Anti-CHRNA4 antibody, EBN antibody, EBN1 antibody, BFNC antibody, NACRA4 antibody, Cholinergic Receptor Nicotinic Alpha 4 antibody
Specificity CHRNA4 antibody was raised against the N terminal of CHRNA4
Cross Reactivity Human,Mouse,Rat
Applications WB
Immunogen CHRNA4 antibody was raised using the N terminal of CHRNA4 corresponding to a region with amino acids AEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTT
Assay Information CHRNA4 Blocking Peptide, catalog no. 33R-1126, is also available for use as a blocking control in assays to test for specificity of this CHRNA4 antibody

Images

Western Blot analysis using CHRNA4 antibody (70R-5185)

CHRNA4 antibody (70R-5185) used at 1 ug/ml to detect target protein.

Specifications

Host Rabbit
Method of Purification Affinity purified
Molecular Weight 67 kDa (MW of target protein)
Form & Buffer Lyophilized powder. Add 50ul distilled water for a 1mg/ml concentration of CHRNA4 antibody in PBS
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1 ug/ml

Storage & Safety

Storage Store at 2-8 deg C for short periods. For longer periods of storage, store at -20 deg C. Avoid repeat freeze-thaw cycles.

General Information

Biological Significance CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described.

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Images

  • Western Blot analysis using CHRNA4 antibody (70R-5185) | CHRNA4 antibody (70R-5185) used at 1 ug/ml to detect target protein.

Availability: In stock

Price: £250.71
Size: 50 ug
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