Chromogranin A antibody (10R-C126a)

Mouse monoclonal Chromogranin A antibody

Synonyms Monoclonal Chromogranin A antibody, Anti-Chromogranin A antibody, CgA antibody
Specificity Human
Cross Reactivity Human, monkey, pig, rabbit, rat
Applications IHC-F, IHC-P, WB
Immunogen Chromogranin A antibody was raised in mouse using human pheochromocytoma as the immunogen.

Images

Immunohistochemical staining using Chromogranin A antibody (10R-C126a)

Formalin-fixed, paraffin-embedded human pancreatic tumor stained with Chromogranin A antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.

Specifications

Host Mouse
Clone LK2H10
Isotype IgG1 kappa
Method of Purification Chromogranin A antibody was purified by Protein A chromatography.
Form & Buffer Antibody purified from ascites fluid by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations IHC-F: 1:800, IHC-P: 1:800, WB: 1-2 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Chromogranin A (a protein of 439-amino acid which is encoded on chromosome 14) is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Coexpression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms.

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Images

  • Immunohistochemical staining using Chromogranin A antibody (10R-C126a) | Formalin-fixed, paraffin-embedded human pancreatic tumor stained with Chromogranin A antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.
  • Immunohistochemical staining using Chromogranin A antibody (10R-C126a) | Formalin-fixed, paraffin-embedded rat pancreas stained with Chromogranin A antibody using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of islet cells.

Availability: In stock

Price: £260.41
Size: 100 ug
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