CNTFR antibody (70R-9962)

Affinity purified rabbit polyclonal CNTFR antibody

Synonyms Polyclonal CNTFR antibody, Anti-CNTFR antibody, ciliary neurotrophic factor receptor antibody, MGC1774 antibody
Cross Reactivity Human
Applications WB
Immunogen CNTFR antibody was raised in rabbit using the C terminal of CNTFR as the immunogen
Assay Information CNTFR Blocking Peptide, catalog no. 33R-1094, is also available for use as a blocking control in assays to test for specificity of this CNTFR antibody

Images

Western Blot analysis using CNTFR antibody (70R-9962)

CNTFR antibody (70R-9962) used at 0.2-1 ug/ml to detect target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types.

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Images

  • Western Blot analysis using CNTFR antibody (70R-9962) | CNTFR antibody (70R-9962) used at 0.2-1 ug/ml to detect target protein.

Availability: In stock

Price: £276.43
Size: 50 ug
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