COL1A1 antibody (70R-9963)

Affinity purified rabbit polyclonal COL1A1 antibody

Synonyms Polyclonal COL1A1 antibody, Anti-COL1A1 antibody, COLA-1, COLA-1 antibody, alpha 1 antibody, collagen, COLA 1 antibody, type I, OI4 antibody, COL1A1, COLA 1
Cross Reactivity Human
Applications WB
Immunogen COL1A1 antibody was raised in rabbit using the C terminal of COL1A1 as the immunogen
Assay Information COL1A1 Blocking Peptide, catalog no. 33R-3394, is also available for use as a blocking control in assays to test for specificity of this COL1A1 antibody

Images

Western Blot analysis using COL1A1 antibody (70R-9963)

Western Blot showing COL1A1 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 0.2-1 ug/ml

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

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Images

  • Western Blot analysis using COL1A1 antibody (70R-9963) | Western Blot showing COL1A1 antibody used at a concentration of 1-2 ug/ml to detect its target protein.

Availability: In stock

Price: £276.43
Size: 50 ug
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