COL4A6 antibody (70R-9964)
Affinity purified rabbit polyclonal COL4A6 antibody
|Synonyms||Polyclonal COL4A6 antibody, Anti-COL4A6 antibody, COL4A6, COLA6-4 antibody, COLA6 4 antibody, alpha 6 antibody, collagen, COLA6 4, type IV, COLA6-4, MGC88184 antibody|
|Immunogen||COL4A6 antibody was raised in rabbit using the middle region of COL4A6 as the immunogen|
|Assay Information||COL4A6 Blocking Peptide, catalog no. 33R-3328, is also available for use as a blocking control in assays to test for specificity of this COL4A6 antibody|
Western Blot analysis using COL4A6 antibody (70R-9964)
Western Blot showing COL4A6 antibody used at a concentration of 1-2 ug/ml to detect its target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.|
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