CRABP1 antibody (10R-1159)

Mouse monoclonal CRABP1 antibody

Synonyms Monoclonal CRABP1 antibody, Anti-CRABP1 antibody, CRABP 1 antibody, CRABP-I antibody, Cellular retinoic acid binding protein 1 CRABP 1 antibody, RBP 5 antibody, CRABP antibody, RBP5 antibody, CRABP -1 antibody, Retinoic acid binding protein I cellular. antibody, CRABP I antibody, CRABPI antibody, CRABP 1, CRABP1, CRABP -1
Specificity Human
Cross Reactivity Human, Mouse
Applications ELISA, WB
Immunogen CRABP1 antibody was raised in mouse using recombinant human CRABP1 (1-137aa) purified from E. coli as the immunogen.

Images

Western Blot analysis of CRABP1 antibody (10R-1159)

The extracts of mouse eye (30 ug) were resolved by SDS-PAGE, transferred to nitrocellulose membrane and probed with anti-human CRABP1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Host Mouse
Clone AT1A1
Isotype IgG2b kappa
Source Anti-human CRABP1 antibody, clone AT1A1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CRABP1 protein.
Method of Purification CRABP1 antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:500-1:1,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance CRABP1 (cellular retinoic acid-binding protein 1) is a member of the specific carrier proteins for members of the vitamin A family. CRABP1 is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. It is constitutively expressed and is believed to have different functions in the cell than the related CRABP2. Interestingly, Sytenol A bakuchiol has very specific receptor specificity over retinol and has no effect on the RAR-beta and RAR-gamma receptors and down-regulates CRABP1.

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Images

  • Western Blot analysis of CRABP1 antibody (10R-1159) | The extracts of mouse eye (30 ug) were resolved by SDS-PAGE, transferred to nitrocellulose membrane and probed with anti-human CRABP1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Availability: In stock

Price: £212.33
Size: 100 ul
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