CXCL1/GRO alpha protein (His tag) (80R-1092)
Purified recombinant Human CXCL1/GRO alpha protein
|Synonyms||fibroblast secretory protein protein, Chemokine (C-X-C motif) ligand 1 protein, MGSA protein, GRO1 protein, SCYB1 protein, CXCL1 protein, Growth-regulated alpha protein protein, FSP protein, , CXCL/GRO alpha 1, CXCL1/GRO alpha, NAP-3 protein, CXCL/GRO alpha-1 protein, SCYB1 protein, GROA protein, CXCL/GRO alpha 1 protein, MGSA-a protein, CXCL/GRO alpha-1, chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity alpha) protein, Chemokine (C-X-C motif) ligand 1 / Growth-regulated alpha protein protein, GRO1 oncogene (melanoma growth stimulating activity alpha) protein|
Coomassie Blue stained SDS-PAGE of CXCL1/GRO alpha protein (His tag) (80R-1092)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||35-107 amino acids: MGSSHHHHHH SSGLVPRGSH MASVATELRC QCLQTLQGIH PKNIQSVNVK SPGPHCAQTE VIATLKNGRK ACLNPASPIV KKIIEKMLNS DKSN|
|Grade & Purity||> 90% pure|
|Molecular Weight||10.1 kDa (94 aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl, pH 8.0, containing 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||CXCL1/GROa is a growth factor for melanoma cells and a chemotaxin for neutrophils. Similar to other alpha chemokines, this protein is potent neutrophil attractant and activator and is also active toward basophils. In addition, CXCL1 protein may be a therapeutic target as well as a diagnostic marker in ovarian cancer. Recombinant CXCL1 protein was expressed in E. coli and purified by using conventional chromatography techniques|
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