CYB5R3 antibody (70R-10194)

Affinity purified rabbit polyclonal CYB5R3 antibody

Synonyms Polyclonal CYB5R3 antibody, Anti-CYB5R3 antibody, B5R antibody, CYBR3-5, CYBR3 5, cytochrome b5 reductase 3 antibody, CYBR3-5 antibody, CYB5R3, DIA1 antibody, CYBR3 5 antibody
Cross Reactivity Human
Applications WB
Immunogen CYB5R3 antibody was raised in rabbit using the C terminal of CYB5R3 as the immunogen
Assay Information CYB5R3 Blocking Peptide, catalog no. 33R-4127, is also available for use as a blocking control in assays to test for specificity of this CYB5R3 antibody

Images

Western Blot analysis using CYB5R3 antibody (70R-10194)

Western Blot showing CYB5R3 antibody used at a concentration of 1 ug/ml against HT1080 Cell Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.

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Images

  • Western Blot analysis using CYB5R3 antibody (70R-10194) | Western Blot showing CYB5R3 antibody used at a concentration of 1 ug/ml against HT1080 Cell Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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