Cyclophilin B antibody (10R-1086)

Mouse monoclonal Cyclophilin B antibody

Synonyms Monoclonal Cyclophilin B antibody, Anti-Cyclophilin B antibody, SCYLP antibody, CYP S1 antibody, 26- 216aa antibody, CYPB antibody, AA553318 antibody, CyP 20b antibody, AA408962 antibody, Cphn2 antibody, peptidyl prolyl cis trans isomerase B antibody, Peptidyl prolyl cis trans isomerase B precursor antibody, Cphn 2 antibody, MGC2224 antibody, Rotamase antibody, S cyclophilin. antibody, Peptidylprolyl isomerase B antibody, PPIB antibody, MGC14109 antibody, AI844835 antibody, CYP-S1: Cyclophilin-B antibody, Cyclophilin B antibody, PPIase antibody
Specificity Human
Cross Reactivity To be determined by end-user.
Applications ELISA, WB
Immunogen Cyclophilin B antibody was raised in mouse using recombinant human Cyclophilin B (26-216aa) purified from E. coli as the immunogen.

Specifications

Host Mouse
Clone k2E2
Isotype IgG1 kappa
Source Anti-human Cyclophilin B antibody, clone k2E2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Cyclophilin B protein.
Method of Purification Cyclophilin B antibody was purified by protein-G affinity chromatography
Form & Buffer Supplied as a liquid in PBS, pH 7.4, with 0.1% NaN3.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations WB: 1:1,000-1:2,000

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Cyclophilin B is necessary for the prolactin-induced proliferation, cell growth, and the nuclear retrotransport of prolactin.

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Availability: In stock

Price: £212.33
Size: 100 ul
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