CYP24A1 antibody (70R-9999)
Affinity purified rabbit polyclonal CYP24A1 antibody
|Synonyms||Polyclonal CYP24A1 antibody, Anti-CYP24A1 antibody, CYP24A1, MGC126274 antibody, MGC126273 antibody, CYPA1 24 antibody, polypeptide 1 antibody, CP24 antibody, CYPA1 24, CYPA1-24 antibody, CYPA1-24, cytochrome P450, CYP24 antibody, family 24, P450-CC24 antibody, subfamily A|
|Immunogen||CYP24A1 antibody was raised in rabbit using the C terminal of CYP24A1 as the immunogen|
|Assay Information||CYP24A1 Blocking Peptide, catalog no. 33R-5247, is also available for use as a blocking control in assays to test for specificity of this CYP24A1 antibody|
Western Blot analysis using CYP24A1 antibody (70R-9999)
Western Blot showing CYP24A1 antibody used at a concentration of 1-2 ug/ml to detect its target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.|
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