CYP2C11 antibody (20R-CR047)
Rabbit polyclonal CYP2C11 antibody
|Synonyms||Polyclonal CYP2C11 antibody, Anti-CYP2C11 antibody, Cytochrome P450 2C11 antibody, Cytochrome P 450 antibody, Cytochrome P450, Cytochrome P 450, Cytochrome P-450 antibody, Cytochrome P-450|
|Cross Reactivity||Rat, cat|
|Immunogen||CYP2C11 antibody was raised in rabbit using Synthetic peptides corresponding to residues D(49) I G Q S I K K F S K V(60) and Q(491) R A D S L S S H L(500) of rat Cytochrome P450 2C11 as the immunogen.|
Immunohistochemical staining using CYP2C11 antibody (20R-CR047)
Immunohistochemistry analysis of Cytochrome P450 2C11 showing positive staining in the cytoplasm of paraffin-treated Rat kidney tissue (right) compared with a negative control in the absence of primary antibody (left). Cytochrome P450 2C11 antibody was used at 1/200 overnight at 4 deg C.
|Form & Buffer||Antiserum diluted in PBS containing 0.05% NaN3.|
Usage & Assay Information
|Usage Recommendations||IHC-F: 1:100, WB: 1:1,500|
Storage & Safety
|Storage||Aliquot and store at -20 deg C. Avoid repeated freeze/thaw cycles.|
|Biohazard Information||This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.|
|Biological Significance||The cytochrome P450 (P450) superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. EET?s are converted from AA by the 2C11 family of P450?s whose expression is induced by testosterone and is therefore not generally found in females.|
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