CYP2E1 antibody (20R-CR053)
Rabbit polyclonal CYP2E1 antibody
|Synonyms||Polyclonal CYP2E1 antibody, Anti-CYP2E1 antibody, Cytochrome P450, Cytochrome P450 2E1 antibody, Cytochrome P 450, Cytochrome P-450 antibody, Cytochrome P-450, Cytochrome P 450 antibody|
|Cross Reactivity||Human, mouse, rat|
|Immunogen||CYP2E1 antibody was raised in rabbit using a synthetic peptide as the immunogen.|
Western blot analysis using CYP2E1 antibody (20R-CR053)
Western Blot Analysis: Human brain lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-Cytochrome P450 CYP2E1 (1:1000 dilution). Proteins were visualized using a donkey anti-rabbit secondary ntibody conjugated to HRP and a chemiluminescence detection system.
|Form & Buffer||Neat serum with no preservatives.|
Usage & Assay Information
|Usage Recommendations||Optimal conditions to be determined by end user|
Storage & Safety
|Storage||Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles|
|Biological Significance||The cytochrome P450 superfamily (officially abbreviated as CYP) is a large and diverse group of enzymes. The function of most CYP enzymes is to catalyze the oxidation of organic substances. The substrates of CYP enzymes include metabolic intermediates such as lipids and steroidal hormones, as well as xenobiotic substances such as drugs and other toxic chemicals. Cytochrome P450 2E1 (abbreviated CYP2E1, EC 188.8.131.52), is involved in the metabolism of xenobiotics in the body. In humans, the CYP2E1 enzyme is encoded by the CYP2E1 gene. While it is involved in the oxidative metabolism of a small range of substrates (mostly small polar molecules), there are many important drug interactions mediated by CYP2E1.|
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