Cytokeratin 18 antibody (10R-C161a)

Mouse monoclonal Cytokeratin 18 antibody

Synonyms Monoclonal Cytokeratin 18 antibody, Anti-Cytokeratin 18 antibody, Keratin K18 antibody, Cytokeratin 18, Cytokeratin -18, Cytokeratin 18, Cytokeratin 18 antibody, Cytokeratin -18 antibody
Specificity Human cytokeratin 18
Cross Reactivity Bovine, dog, fish, hamster, human, mouse, pig, rat, sheep, trout, zebrafish
Applications IHC-F, IHC-P, WB
Immunogen Cytokeratin 18 antibody was raised in mouse using human cytokeratin 18 from HeLa cytoskeletal preparation as the immunogen.

Specifications

Host Mouse
Clone Ks18.04
Isotype IgG1
Method of Purification Protein A affinity chromatography
Form & Buffer Supplied as a lyophilized powder. Reconstitute in 1 ml dist. water (final solution contains 0.09 % NaN3, 0.5% BSA in PBS buffer, pH 7.4)

Usage & Assay Information

Usage Recommendations IHC-P: 1:20

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin represents an excellent marker for the discrimination of specific subtypes of adenocarcinoma. Keratin 18 is a type I cytokeratin. It is, together with its filament partner keratin 8, perhaps the most commonly found products of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.

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Availability: In stock

Price: £236.37
Size: 50 ug
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