Cytokeratin 7 antibody (10R-C174b)

Mouse monoclonal Cytokeratin 7 antibody

Synonyms Monoclonal Cytokeratin 7 antibody, Anti-Cytokeratin 7 antibody, Cytokeratin 7, Cytokeratin 7, Cytokeratin -7 antibody, Cytokeratin -7, Keratin K7 antibody, Cytokeratin 7 antibody
Specificity human cytokeratin 7
Cross Reactivity Hamster, human, mouse
Applications IHC-F, IHC-P, WB
Immunogen Cytokeratin 7 antibody was raised in mouse using Cell line T24 ( human bladder carcinoma) as the immunogen.

Specifications

Host Mouse
Clone OVTL 12-30
Isotype IgG1 kappa
Grade & Purity Culture supernatant
Form & Buffer Supplied as cell culture supernatant with 0.09% NaN3.

Usage & Assay Information

Usage Recommendations IHC-F: 1:5-1:10, IHC-P: 1:5-1:10

Storage & Safety

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

General Information

Biological Significance Decorates specific subtypes of adenocarcinoma. Keratin K7 is found in the columnar and glandular epithelium of the lung, cervix, breast, bile ducts, larger collecting ducts of the kidney and in mesothelium, but is normally absent from gastrointestinal epithelium, hepatocytes and myoepithelium. Several types of adenocarcinomas of the urinary tract are negative, while adenocarcinomas of the mammary gland, ovary and lung are positive. In colorectal carcinoma early stages are reported to be negative but advanced stages of tumor development are positive for keratin K7 expression.

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Availability: In stock

Price: £332.52
Size: 1 ml
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