DCUN1D1 protein (His tag) (80R-1642)
Purified recombinant Human DCUN1D1 protein
|Synonyms||DCUND-1, SCCRO protein, DCUND 1, Tes3, DCN1-like protein 1 protein, DCUND-1 protein, RP42 protein, DCUND 1 protein, SCRO protein, DCUN1L1 protein, DCUN1D1|
Coomassie Blue stained SDS-PAGE of DCUN1D1 protein (His tag) (80R-1642)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-259 amino acids: MGSSHHHHHH SSGLVPRGSH MNKLKSSQKD KVRQFMIFTQ SSEKTAVSCL SQNDWKLDVA TDNFFQNPEL YIRESVKGSL DRKKLEQLYN RYKDPQDENK IGIDGIQQFC DDLALDPASI SVLIIAWKFR AATQCEFSKQ EFMDGMTELG CDSIEKLKAQ IPKMEQELKE PGRFKDFYQF TFNFAKNPGQ KGLDLEMAIA YWNLVLNGRF KFLDLWNKFL LEHHKRSIPK DTWNLLLDFS TMIADDMSNY DEEGAWPVLI DDFVEFARPQ IAGTKSTTV|
|Grade & Purity||> 90% pure|
|Molecular Weight||32.2 kDa (279aa), confirmed by MALDI-TOF|
|Form & Buffer||Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 10% glycerol and 0.1M NaCl.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Biological Significance||DCUN1D1, also known as DCN1-like protein 1, is involved in the malignant transformation of squamous cell lineage. This protein regulates Gli1, a key regulator of the hedgehog (HH) pathway that plays an important role in development, maintenance, and regeneration of almost all adult tissues. Recombinant human DCUN1D1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.|
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