Desmoplakin antibody (20R-DP002)

Guinea Pig polyclonal Desmoplakin antibody

Synonyms Polyclonal Desmoplakin antibody, Anti-Desmoplakin antibody
Specificity Human desmoplakin 1
Cross Reactivity To be determined by end-user
Applications IF, IHC-F, IHC-P, WB
Immunogen Desmoplakin antibody was raised in guinea pig using the C-terminus of recombinant human desmoplakin 1 as the immunogen.

Specifications

Host Guinea Pig
Grade & Purity > 95% pure
Form & Buffer Supplied as stabilized antiserum.

Usage & Assay Information

Usage Recommendations IF: 1:100, IHC-P: 1:50, WB: 1:1,000

Storage & Safety

Storage Store at 4 deg C.

General Information

Biological Significance Desmoplakin is a protein associated with desmosomes. Desmoplakin is a protein that in humans is encoded by the DSP gene. Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques. The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin.

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Availability: In stock

Price: £316.49
Size: 50 ul
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