EDN3 antibody (70R-10261)

Affinity purified rabbit polyclonal EDN3 antibody

Synonyms Polyclonal EDN3 antibody, Anti-EDN3 antibody, ET3 antibody, EDN-3, MGC61498 antibody, EDN 3 antibody, EDN3, MGC15067 antibody, EDN 3, endothelin 3 antibody, EDN-3 antibody
Cross Reactivity Human
Applications WB
Immunogen EDN3 antibody was raised in rabbit using the C terminal of EDN3 as the immunogen
Assay Information EDN3 Blocking Peptide, catalog no. 33R-5011, is also available for use as a blocking control in assays to test for specificity of this EDN3 antibody

Images

Western Blot analysis using EDN3 antibody (70R-10261)

Western Blot showing EDN3 antibody used at a concentration of 1 ug/ml against Fetal Kidney Lysate

Specifications

Host Rabbit
Form & Buffer Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration 1 mg/ml

Usage & Assay Information

Usage Recommendations Optimal conditions to be determined by the end user

Storage & Safety

Storage Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.

General Information

Biological Significance The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

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Images

  • Western Blot analysis using EDN3 antibody (70R-10261) | Western Blot showing EDN3 antibody used at a concentration of 1 ug/ml against Fetal Kidney Lysate

Availability: In stock

Price: £276.43
Size: 50 ug
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