eIF4EBP1 protein (His tag) (80R-1191)
Purified recombinant Human eIF4EBP1 protein
|Synonyms||eukaryotic translation initiation factor 4E binding protein 1 protein, eIF4EBP1, eIFEBP1 4 protein, phosphorylated heat- and acid-stable protein regulated by insulin 1 protein, EIF4EBP1 protein, eIFEBP1-4, MGC4316 protein, BP-1 protein, eIFEBP1 4, eIFEBP1-4 protein, PHAS-I protein, , 4EBP1 protein, Eukaryotic translation initiation factor 4E-binding protein 1 protein, 4E-BP1 protein|
Coomassie Blue stained SDS-PAGE of eIF4EBP1 protein (His tag) (80R-1191)
Figure annotation denotes ug of protein loaded and % gel used.
|Residues||1-118 amino acids: MGSSHHHHHH SSGLVPRGSH MSGGSSCSQT PSRAIPATRR VVLGDGVQLP PGDYSTTPGG TLFSTTPGGT RIIYDRKFLM ECRNSPVTKT PPRDLPTIPG VTSPSSDEPP MEASQSHLRN SPEDKRAGGE ESQFEMDI|
|Grade & Purity||> 95% pure|
|Molecular Weight||14.7 kDa (138aa), confirmed by MALDI-TOF. (Molecular weight on SDS-PAGE will appear higher)|
|Form & Buffer||Liquid in PBS, pH 7.4, with 10% glycerol.|
Storage & Safety
|Storage||Store at 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles.|
|Endotoxin Levels||< 1.0 EU per ug of protein (determined by LAL method)|
|Biological Significance||eIF4E-BP1, also known as eukaryotic translation initiation factor 4E-binding protein 1, is a member of a family of translation repressor proteins. This protein regulates eukaryotic translation initiation factor 4E (eIF4E) activity by preventing its assembly into the eIF4F complex and mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. Recombinant EIF4EBP1 protein was expressed in E. coli and purified by using conventional chromatography techniques.|
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