Eotaxin protein (Mouse) (30R-AE019)

Purified recombinant Mouse Eotaxin protein

Synonyms Small inducible cytokine A11 protein, SCYA11 protein, Eosinophil chemotactic protein protein, CCL11 protein, Mouse CCL11 protein, chemokine (C-C motif) ligand 11 protein, Murine Eotaxin protein
Species Mouse
Protein Type Recombinant
Applications User optimized

Specifications

Residues Eotaxin Mouse protein containing 74 amino acids.
Expression System E.coli
Grade & Purity > 95% pure
Form & Buffer Supplied as a lyophilized powder.

Usage & Assay Information

Bioactivity The biological activity was determined by measuring the dose dependent phosphorylation of ERK1 and ERK2 in CCR3 transfected 293 cells. Significant ERK phosphorylation is observed with >100 ng/ml of recombinant mouse eotaxin.

Storage & Safety

Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

General Information

Biological Significance Chemokine (C-C motif) ligand 11 (CCL11) is a small cytokine belonging to the CC chemokine family that is also known as eotaxin. CCL11 selectively recruits eosinophils by inducing their chemotaxis, and therefore, is implicated in allergic responses. The effects of CCL11 are mediated by its binding to a G-protein-linked receptor known as a chemokine receptor. Chemokine receptors for which CCL11 is a ligand include CCR2, CCR3 and CCR5. The gene for human CCL11 (scya11) is encoded on three exons and is located on chromosome 17.

References
Add a Paper

Sorry, but there are no references currently for this product.

Reviews

You need to be logged in to write a review. Please login here

Sorry there are currently no reviews for this product

Availability: In stock

Price: £180.28
Size: 20 ug
OR
Shipping
View Our Distributors