ErbB-2 + HER-2 + Neu antibody (10R-C100aX)

Rabbit monoclonal ErbB-2 + HER-2 + Neu antibody

Synonyms Monoclonal ErbB-2 + HER-2 + Neu antibody, Anti-ErbB-2 + HER-2 + Neu antibody, ERBB 2, ERBB -2, ErbB-2 (HER-2/Neu) antibody, ERBB 2 antibody, ERBB2, ERBB -2 antibody
Specificity Human
Cross Reactivity To be determined by end-user
Applications IHC-F, IHC-P
Immunogen ErbB-2/HER-2/Neu antibody was raised in rabbit using recombinant protein encoding extracellular domain of human c-erbB2 as the immunogen.

Images

Immunohistochemical staining using ErbB-2 + HER-2 + Neu antibody (10R-C100aX)

Specifications

Host Rabbit
Clone SP3
Isotype IgG
Molecular Weight 185 kDa (predicted detection band MW)
Form & Buffer Tissue culture supernatant with 15mM NaN3.
Concentration Batch dependent - please inquire should you have specific requirements

Usage & Assay Information

Usage Recommendations IHC-F: 1:200, IHC-P: 1:200

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance HER2 gene encodes a transmembrane glycoprotein with tyrosine kinase activity. It is closely related in structure to the epidermal growth factor receptor c-erbB-3/HER3/neu oncoprotein. The protein is detectable in a subset of breast and other carcinomas (urinary bladder, stomach, lung, endometrium and ovary). In the case of breast cancer, over expression determined by immunohistochemistry has been shown to be associated with poor prognosis and an indication to initiate trastuzumab/herceptin therapy.

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Images

  • Immunohistochemical staining using ErbB-2 + HER-2 + Neu antibody (10R-C100aX) |

Availability: In stock

Price: £1,037.62
Size: 500 ul
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