Estrogen Receptor antibody (10R-E118a)

Mouse monoclonal Estrogen Receptor antibody

Synonyms Monoclonal Estrogen Receptor antibody, Anti-Estrogen Receptor antibody, DKFZp686N23123 antibody, ESR-1 antibody, Era antibody, ESR antibody, ESR 1 antibody, ESRA antibody
Cross Reactivity Chicken, cow, dog, hamster, human, mouse, pig, rabbit, rat, sheep
Applications Gel Shift, IP, WB
Immunogen Estrogen receptor antibody was raised in mouse using 35 kDa, C-terminal fragment (aa 302-595) of human ER expressed in E.coli as the immunogen.

Specifications

Host Mouse
Clone TE111.5D11
Isotype IgG1
Method of Purification Estrogen Receptor antibody was purified by Protein A chromatography.
Molecular Weight 67 kDa (predicted detection band MW)
Form & Buffer Antibody purified from a bioreactor concentrate by protein G chromotography and supplied in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% NaN3.
Concentration 0.2 mg/ml

Usage & Assay Information

Usage Recommendations Gel Shift: 1 mg/ml, IP: 2 ug/mg, WB: 1-2 ug/ml

Storage & Safety

Storage Store at 4 deg C.
Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

General Information

Biological Significance Estrogen receptor, a member of the steroid receptor superfamily, contains highly conserved DNA binding and ligand binding domains. Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER alpha regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery.

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Availability: In stock

Price: £361.36
Size: 100 ug
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