F2RL2 antibody (70R-9968)
Affinity purified rabbit polyclonal F2RL2 antibody
|Synonyms||Polyclonal F2RL2 antibody, Anti-F2RL2 antibody, FRL 2, FRL 2 antibody, thrombin receptor-like 2 antibody, coagulation factor II, PAR3 antibody, FRL-2 antibody, FRL-2, F2RL2|
|Immunogen||F2RL2 antibody was raised in rabbit using the C terminal of F2RL2 as the immunogen|
|Assay Information||F2RL2 Blocking Peptide, catalog no. 33R-7108, is also available for use as a blocking control in assays to test for specificity of this F2RL2 antibody|
Western Blot analysis using F2RL2 antibody (70R-9968)
F2RL2 antibody (70R-9968) used at 0.2-1 ug/ml to detect target protein.
|Form & Buffer||Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.|
Usage & Assay Information
|Usage Recommendations||WB: 0.2-1 ug/ml|
Storage & Safety
|Storage||Store at 4 deg C, following reconstitution, aliquot and store at -20 deg C. Avoid repeated freeze-thaw cycles.|
|Biological Significance||Coagulation factor II (thrombin) receptor-like 2 (F2RL2) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL2 is also a member of the protease-activated receptor family and activated by thrombin. F2RL2 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL2 is a cofactor for F2RL3 activation by thrombin. It mediates thrombin-triggered phosphoinositide hydrolysis and is expressed in a variety of tissues.|
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